PS-341 (MG-341)

●Purchase●DescriptionPS-341(Pyz-Phe-boroLeu)istheactiveingredientinBortezomib

产品型号：27715-1
厂商性质：生产厂家
更新时间：2023-12-19
访问量：139

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Description

PS-341 (Pyz-Phe-boroLeu) is the active ingredient in Bortezomib. PS-341 is a reversible, cell permeable, potent, and selective proteasome inhibitor (Ki=0.6 nM). It binds the catalytic site of the 26S proteasome with high affinity and specificity. Inhibits proliferation of a number of tumor cell lines (IC50=7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis.

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Synonyms

Pyz–Phe–boroLeu, N–(2–pyrazine)carbonyl–L–phenylalanyl–L–leucyl boronic acid

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PS-341 (MG-341)

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