NY-ESO-1 TCR (1G4) CD8+ NFAT-Luciferase Reporter Jurkat Cell Line

This cell line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and NY-ESO-1 TCR (1G4) using lentiviral transduction (CD8a Lentivirus #78648 and NY-ESO-1 -Specific TCR Lentivirus Clone 1G4 #78675). The human TCR clone 1G4 specifically recognizes antigen NY-ESO-1 (New York esophageal squamous cell carcinoma 1).

Figure 1: Illustration of the functional co-culture assay used to validate the NY-ESO-1 TCR (1G4) CD8+ NFAT-Luciferase Reporter Jurkat cell line.

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