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●Purchase●DescriptionTheCas9Inducible(Tet-On)iPSCellPoolexpressestheCas9(StreptococcuspyogenesCRISPRassociatedprotein9)geneunderthecontrolofatightTREtetracycline-induciblepromoter
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The Cas9 Inducible (Tet-On) iPS Cell Pool expresses the Cas9 (Streptococcus pyogenes CRISPR associated protein 9) gene under the control of a tight TRE tetracycline-inducible promoter, introduced into PBMC-derived human iPS cells via lentiviral transduction [Cas9 Lentivirus (inducible TET on), BPS Bioscience #78794]. Cas9 expression can be induced with doxycycline treatment, allowing temporal control of its expression. Cas9 Inducible (Tet-On) iPS cells can be transduced with single-guide RNA (sgRNA) targeting gene(s) of interest to generate genetically engineered cell pools or cell lines.
Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.