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EPZ-6438

●Purchase●DescriptionEPZ-6438isapotentandbio-availableinhibitorofEZH2

  • 产品型号:27626-3
  • 厂商性质:生产厂家
  • 更新时间:2023-11-11
  • 访  问  量:94
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Description

EPZ-6438 is a potent and bio-available inhibitor of EZH2, the catalytic subunit of polycomb repressive complex 2 (PRC2) catalyzing the methylation of lysine 27 of histone H3 (H3K27), that inhibits the activity of human PRC2-containing wild-type EZH2 (Ki = 2.5 nM).

Synonyms
E-7438; N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl(oxan-4-yl)amino]-2-methyl-5-[4-(morpholin-4-ylmethyl)phenyl]benzamide
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