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I-BET151 (GSK1210151A)

●Purchase●DescriptionI-BET151(GSK1210151A)isaBETbromodomaininhibitor

  • 产品型号:27629-3
  • 厂商性质:生产厂家
  • 更新时间:2023-11-11
  • 访  问  量:88
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Description

I-BET151(GSK1210151A) is a BET bromodomain inhibitor. I-BET151 displays potent binding affinity to BRD2, BRD3 and BRD4 with Kd of 0.02-0.1 µM. I-BET151 (0.5 or 5 µM) inhibits the binding of BETs (BRD2, BRD3, BRD4, and BRD9) but not the binding of 23 other bromodomain proteins. I-BET151 also blocks recruitment of BET to chromatin.

This product has been cited 1 time.

Synonyms
I-BET151; GSK1210151A; 7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one
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