The Firefly Luciferase Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by a UbC (ubiquitin C) promoter. The ubiquitin C promoter is useful for high-level expression across a broad range of species and tissue types.