AAV8 Luciferase-mCherry

保存条件：-80°C(dryice)保质期：3-18month英文名：AAV8Luciferase-mCherry数量：1供应商：BPSBioscienceInc

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厂商性质：生产厂家
更新时间：2023-10-10
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详细介绍

保存条件：
-80°C (dry ice)
保质期：
3-18 month
英文名：
AAV8 Luciferase-mCherry
数量：
1
供应商：
BPS Bioscience Inc.
CAS号：
/
规格：
50 µl x 2

Adeno-Associated Virus serotype 8 (AAV8) was isolated from rhesus monkey tissue, and the AAV8 rep and cap nucleotide sequences have 88% homology with AAV7 and 82% with AAV2. AAV8 exhibits greater transduction efficiency in the liver than other AAV serotypes. AAV8 and 9 have recently been used to correct disease-causing mutations and improve muscle function in mouse models of Duchenne muscular dystrophy.These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript and expression of luciferase and mCherry as two separate proteins.

温馨提示：不可用于临床治疗。

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