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BPS Bioscience的PCSK9筛选和检测服务

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  • 更新时间:2023-12-19
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    BPS Bioscience

  • 服务名称:

    BPS Bioscience的PCSK9筛选和检测服务

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a critical regulator of cholesterol metabolism through its interaction with the hepatic LDL receptor (LDLR). PCSK9 is an endopeptidase that binds to the EGFR-like domain of LDLR, leading to LDLR degradation, which in turn, results in increased circulating LDL. Inhibiting the PCSK9-LDLR interaction is an increasingly desirable therapeutic approach for lowering LDL-cholesterol levels to replace or supplement statins. New therapies are critical for addressing atherosclerosis, stroke, heart disease, and other cardiovascular disorders.

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We offer rapid and dependable screening and profiling services for PCSK9:LDLR inhibitors. Our team of experts, using our in-house developed biochemical assay kits, can provide:

  • Screening for active compounds (small molecules, peptides, or antibodies)

  • Determination of IC50

  • Project guidance and questions answered in a timely manner

  • Delivery of detailed results promptly and on time

Available Service Assays

PCSK9:LDLRPCSK9 (D374T):LDLR

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