NLG919

保存条件：-80°C(dryice)保质期：Storeassuppliedatorbelow-20°Cforupto3years

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厂商性质：生产厂家
更新时间：2023-12-19
访问量：157

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详细介绍

保存条件：
-80°C (dry ice)
保质期：
Store as supplied at or below -20°C for up to 3 years. Stable in DMSO at -80°C for up to 6 months.
英文名：
NLG919
数量：
1
供应商：
BPS Bioscience Inc.
CAS号：
/
规格：
10 mg

NLG919 is an orally available potent inhibitor of the indoleamine-2,3-dioxygenase (IDO1) pathway, a crucial pathway involved in allergic inflammation that mediatesimmunosuppressive effects through metabolization of tryptophan to kynurenine. NLG919affects differentiation and proliferation of T cells by inducing downstream signaling via GCN2,mTOR and AHR, with values of Ki = 7 nM and EC50 = 75 nM. NLG919 is being investigated forthe treatment of immunosuppression associated with cancer.

温馨提示：不可用于临床治疗。

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NLG919

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